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The most common mechanism of colistin resistance
2018-10-22
The most common mechanism of colistin resistance is modification of LPS, a component of cell membrane, which is the first site of action of colistin. To determine whether inner and outer membranes were still present or intact in Col-R and Col-D A. baumannii strains, we visualized the 2 Col-S, 2 Col-
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The challenge of developing adaptive responsive low energy a
2018-10-22
The challenge of developing adaptive, responsive low-energy architecture requires new knowledge about the complex and dynamic interaction between envelope geometry and optimisation of performance metrics (Hudson, 2008). In this paper, we present the results of a building envelope tessellation study
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br Osteochondritis dissecans OCD is a subchondral bone
2018-10-22
Osteochondritis dissecans (OCD) is a subchondral bone lesion that mainly affects juveniles and young adults. Healing rates of stable OCD lesions treated by nonoperative methods are reported to be between 50% and 94%. The clinical staging system of OCD is mainly based on the findings of arthroscopy
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Two days before the scheduled surgery however the patient wa
2018-10-22
Two days before the scheduled surgery, however, the patient was brought to the emergency room with severe headache and fever. She was initially alert but rapidly deteriorated and had a Glasgow Coma Scale score of E3M4V1. The pupils were dilated bilaterally and without light reflex. Brain computed to
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br Patients and methods br Results Patient characteristics a
2018-10-22
Patients and methods Results Patient characteristics and clinical outcomes are summarized in Table 1. The operative times were 232 minutes, 220 minutes, and 139 minutes. No measurable blood loss, postoperative bleeding, nerve injury, or dural tear was encountered. Postoperative MRI showed that
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Approximately one decade ago the safety of RFA
2018-10-22
Approximately one decade ago, the safety of RFA was questioned after the reported occurrence of neoplastic seeding in 4 (12.5%) of 32 patients with HCC. However, several investigators reported lower incidence rates that ranged from 0% to 0.9%. Jun Imamura et al recently detected neoplastic seeding i
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notch signaling pathway br Case Report A day old male child
2018-10-22
Case Report A 5-day-old male child, weighing 2.5 kg, was admitted in the emergency department with complaints of an inability to pass meconium, severe abdominal distension, and bilious vomiting. The child had passed meconium once within 24 hours of life. On examination, the heart rate was 140 bea
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br Diagnosis of EGJ cancer
2018-10-22
Diagnosis of EGJ cancer Extensive preoperative staging is essential for the correct selection of a suitable therapeutic strategy against EGJ cancer. Endoscopic ultrasonography (EUS) is the most accurate method for assessing the locoregional extent of metforman and EGJ carcinomas. The EUS accurac
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Lai et al investigated the inhibitory effects
2018-10-22
Lai et al. [52] investigated the inhibitory effects of xanthigen, fucoxanthin, and punicic niclosamide (70% in pomegranate seed oil) on the differentiation of 3T3-L1 preadipocytes. Xanthigen potently and dose-dependently suppressed accumulation of lipid droplets in adipocytes compared to its indivi
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GFP expressing Rhesus nhpESC lines Table
2018-10-22
GFP-expressing Rhesus nhpESC lines (Table 1) used in the aggregation chimera assay produced expanded mouse blastocysts with GFP-expressing nhpESC lines 2706 and 3006 associated with the blastocyst inner cell mass (ICM) cells. We typically combined mouse zona pellucida-free 2-to-8-cell stage embryos
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br Discussion We have described
2018-10-22
Discussion We have described an approach that achieves inducible, retrovirus-mediated gene expression by using the coding sequence of TFs fused to an ERT2 motif. Fusion of the ERT2 motif to two TFs that regulate fate-choice decisions in the course of adult neurogenesis (i.e., ASCL1 and NEUROD1) a
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We also propose that the KIT
2018-10-22
We also propose that the KIT/FGFR2b pathway likely integrates with other signaling pathways to direct progenitor expansion. For example, WNT signaling has been proposed to be a master regulator of lung development (Rajagopal et al., 2008). Yet, our data suggest that WNT and KIT/FGFR2b can affect dis
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Induced pluripotent stem cells iPSCs have the
2018-10-22
Induced pluripotent stem CB-5083 (iPSCs) have the characteristics of human embryonic stem cells (hESCs), and many studies have investigated the similarities between iPSCs and hESCs, including genome stabilities, transcriptome (Chin et al., 2009; Guenther et al., 2010; Newman and Cooper, 2010; Wang
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Interestingly Prominin is found in
2018-10-22
Interestingly, Prominin1 is found in other adult stem cell populations, such as those in the hematopoietic system and small intestine (Snippert et al., 2009; Zhu et al., 2009) and is a marker of tumor-initiating Betulinic Acid manufacturer in several cancers (Neuzil et al., 2007). It was originally
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In RPE transplantation it is widely accepted that
2018-10-22
In RPE transplantation, it is widely accepted that grafted Ozanimod manufacturer perform better in terms of their morphology, physiology, and survival when transplanted as sheets rather than in suspension. It appears that environmental factors provided by cell sheets, such as extracellular matrix a
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