• Air pollution also has a substantial effect on the

  2019-06-29

  

  Air pollution also has a substantial effect on the wellbeing of people worldwide. This pollution can consist of sulfur dioxide, ozone, nitrogen dioxide, and fine-particulate Vinblastine sulfate structure of less than 2·5 μm in diameter (PM). 92% of the global population is exposed to higher-than-re

• Of indicators in the Index ten

  2019-06-28

  

  Of 101 indicators in the Index, ten fulfilled all comparability criteria for the detailed longitudinal analysis, and six core-scored indicators with the highest correlation with overall scores were used for the detailed longitudinal analysis. We made several important observations. First, the crude

• El eje dram tico de En

  2019-06-28

  

  El eje dramático de En la prisión… se va desarrollando Clotrimazole través de los relatos que el Profesor, un militante de la vanguardia política revolucionaria cubana, sueña que, a su vez sueña, que narra a un grupo de “negros” durante un agobiante verano habanero de los años noventa. Todo sucede d

• Ranolazine Patient a year old man with RAEB

  2019-06-28

  

  Patient 2, a 54-year-old man with RAEB 2, and severe chronic obstructive pulmonary disease, struggled through induction chemotherapy with daunorubicin plus cytarabine (DA) 3+10. Second DA 3+8 produced delayed hematopoietic recovery. CR1 was documented after course 1 and lasted 18 months. Relapse was

• br Conflict of interest br Introduction Acute kidney

  2019-06-28

  

  Conflict of interest Introduction Acute kidney injury in patients who are receiving anti-cancer treatments is an uncommon but serious complication. Such injury is often induced by nephrotoxic agents or urinary tract obstruction by space-occupying lesions. Among the many possible causes for ren

• In an effort to determine whether the primary tumour

  2019-06-28

  

  In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi

• A review by Keung and colleagues summarized cases of hematol

  2019-06-28

  

  A 2002 review by Keung and colleagues summarized cases of hematologic malignancy in patients with KS reported between 1961 and 2002 [3]. They described 12 cases of AML in KS in the literature during that time period. Based on the review of the current literature, we found approximately 10 additional

• The recently published global consensus recommendations on p

  2019-06-28

  

  The recently published global consensus recommendations on prevention and management of rickets advocate for the eradication of rickets and osteomalacia through implementation of national supplementation and food fortification programmes containing vitamin D, calcium, or both. On the basis of high-q

• Intrahepatic cholangiocarcinoma ICC originates from the smal

  2019-06-28

  

  Intrahepatic cholangiocarcinoma (ICC) originates from the small intrahepatic ductules or the large intrahepatic ducts proximal to the bifurcation of the right and left hepatic ducts. ICC is the second most common primary malignancy of the liver after hepatocellular carcinoma (HCC). Given the rising

• The status of Fas and Fas ligand

  2019-06-28

  

  The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma. These results suggest that the evaluation of Fas and Fas ligand expression potentially has a significant prognostic value for DFS of HCC patients, in addition to patient clinical stage, and can be regarde

• br Conflict of interest br Introduction Histopathology invol

  2019-06-28

  

  Conflict of interest Introduction Histopathology involves the use of dyes for microscopic examination of tissues in part to spot signs and characteristic features of diseases. Recently, computer assisted diagnosis (CAD) has been widely used in developed countries. In general, it is well-recogn

• br Conclusions and future perspectives br Conflict of intere

  2019-06-28

  

  Conclusions and future perspectives Conflict of interest Author’s contributions Introduction Sulfotransferase (SULT)-mediated sulfation and steroid sulfatase (STS)-mediated desulfation represent two opposing mechanisms involved in regulating the chemical and functional homeostasis of end

• MCs play a key role in the maintaining homeostasis

  2019-06-28

  

  MCs play a key role in the maintaining homeostasis of tissues where they reside by participating in tissue repair, reactions against viral and parasitic infections, and aiding in the regulation of various cell types such as dendritic cells, T cells, and macrophages. In addition, MCs are involved in

• Furthermore an observational cross sectional case control st

  2019-06-27

  

  Furthermore, an observational, cross-sectional case-control study used by the authors of 976 children aged 6–10 years, from an area of small towns immersed in the countryside in central Italy, estimated the rate of FAS as between 4 per 1000 and 12 per 1000 people in 2011. These rates cannot in any c

• br Do we need complete isolation of all PVs in

  2019-06-27

  

  Do we need complete isolation of all PVs in every patient? Circumferential PVI results in satisfactory outcomes for ablation of paroxysmal AF, and electrical isolation of all PVs is currently a standard approach to the treatment of AF, as recommended by the expert consensus statement [6]. Complet

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