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br Communication The first area of precise
2018-11-07
Communication The first area of precise communication is internal to the field. Authors, reviewers, editors, and journals should provide and demand much more precise reporting in papers, and a suite of associated practices which will facilitate cumulative progress. One step in particular we now f
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The multidimensional nature of SES measures can make it diff
2018-11-07
The multidimensional nature of SES measures can make it PLX-4720 difficult to identify the specific mechanisms linking SES to developmental outcomes. In this study, SES may index infants’ early mental abilities/IQs, which in turn contribute to learning and memory efficacy. In this case, the current
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Taken together our study shows that
2018-11-07
Taken together, our study shows that different cognitive profiles emerge in children with CU traits and specific neurodevelopmental disorders, which may have implications for identification of further cognitive strengths and weaknesses and subsequent targeting of specific treatment strategies. Our f
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br Given the continuous improvement
2018-11-06
Given the continuous improvement of basic theories of graphics in modern times, the discipline of perspective underwent a considerable development in the 18th and 19th centuries, 70 years after the publication of Shi Xue. During this period, British and German geometricians examined the resolution
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Intestinal fatty acid binding protein IFABP
2018-11-06
Intestinal fatty acid-binding protein (IFABP), which is a small cytoplasmic protein specifically localized in small bowel enterocytes and involved in fatty stearoyl-coa desaturase transport, is normally undetectable in plasma. In healthy adults, small bowel hypoperfusion during submaximal effort was
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br Discussion Anastomotic aneurysm formation following extra
2018-11-06
Discussion Anastomotic aneurysm formation following extracranial-intracranial (EC-IC) surgery is relatively uncommon. In previously reported cases (Table 1), pseudoaneurysm formation was mostly observed during the first 2 postoperative months, whereas true aneurysms were observed years after surg
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Vitamin A is toxic in
2018-11-06
Vitamin A is toxic in high amounts. But, the provitamins such as carotene are not toxic. It is reported that doses such as 40,000–50,000 and 25,000 IUs are toxic for adults and children respectively [2]. So, it is recommended to use β-carotene for fortification of dairy products. Health risks begin
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br Materials and methods br
2018-11-06
Materials and methods Histopathology Studies Subsequent to blood sample for the biochemical analysis, the animals were forfeit, quickly dissected. A tiny portion of pancreases was engaged and fixed in 10% formalin. The specimen was dehydrated in ascending grades of ethanol, clean in xylene and
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The majority of animals used are
2018-11-06
The majority of animals used are rodents and to derive statistically significant results the numbers of animals needed for testing are enormous with an estimation of 7000 animals and tens of millions of dollars for each test order 7-Nitroindazole in the pharmaceutical industry [141]. Although the nu
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There are several reports that demonstrate roles
2018-11-06
There are several reports that demonstrate roles for Rad51 in addition to its participation in classical HR-mediated DSB repair. For example, in Saccharomyces cerevisiae that lack telomerase or certain telomere binding proteins, the telomeres can be maintained in rare survivors by alternative recomb
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Importantly our findings define a
2018-11-06
Importantly, our findings define a role for NCPCs in promoting skin repair. How then do NCPCs regulate skin repair? Based upon work in strontium chloride (Kumar and Brockes, 2012), we propose that following injury, nerve-derived, Sox2-positive NCPCs proliferate and migrate together with adjacent me
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As a component of the gene targeting strategy used
2018-11-06
As a component of the gene-targeting strategy used to delete Nanog, a neomycin-resistance gene was placed under control of its endogenous promoter (Chambers et al., 2007). Thus, selection with the neomycin analog G418 could be used to rule out the unlikely possibility that undifferentiated pluripote
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With regard to safety issues prolonged differentiation Brede
2018-11-06
With regard to safety issues, prolonged differentiation (Brederlau et al., 2006; Doi et al., 2012) and purification of neurally committed cells (Fukuda et al., 2006; Pruszak et al., 2009; Sundberg et al., 2013) have been attempted to reduce the risk of tumor formation. Recently, a dual SMAD inhibiti
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The following are the supplementary data related to
2018-11-06
The following are the supplementary data related to this article. Introduction Materials and methods Results Discussion Within the human body, three mechanisms of blood vessel formation can be distinguished, namely vasculogenesis, arteriogenesis and angiogenesis. In particular angiogene
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Introduction Since the discovery that somatic cells could be
2018-11-06
Introduction Since the discovery that somatic cells could be reprogrammed to induced pluripotent stem cells (iPSCs) (Takahashi and Yamanaka, 2006), many different pathways have been created based on Waddington\'s Bioactive Compound Library of the “epigenetic landscape”, the model used to illustrat
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