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br Study limitations Although the number
2019-05-17
Study limitations Although the number of CPVT patients enrolled in the present study was small, we documented clearly discernible effects of flecainide on CPVT during exercise testing. The dose of flecainide was adjusted to increase it to the maximum tolerable dose without monitoring serum concen
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Histone Compound Library At baseline the patient exhibited n
2019-05-17
At baseline, the patient exhibited normal A–H (57ms) and H–V (44ms) intervals, with a sinus Histone Compound Library length of 784ms. Both antegrade and retrograde dual atrioventricular (AV) nodal physiologies were assessed by atrial and ventricular extrastimulus (Fig. 2), without inducible AV noda
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The exact incidences of amiodarone induced hyperthyroidism
2019-05-17
The exact incidences of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism currently remain unknown; however, the reported frequencies of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism vary widely from 0.8% to 37.8% [7–16] and from 1% to 32% [13,17–20]
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br Discovery of S PR as a
2019-05-17
Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than
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PCI-32765 br zoonoses are responsible for a staggering billi
2019-05-17
13 zoonoses are responsible for a staggering 2·2 billion human illnesses and 2·3 million deaths per year, mostly in low-income and middle-income countries () where the correlation between rates of protein malnutrition and incidence of endemic zoonotic diseases is 99%. Veterinary medicine has an i
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br Cholera remains a serious global public health problem di
2019-05-16
Cholera remains a serious global public health problem, disproportionately affecting poor individuals, causing illness and death for thousands of people each year. Cholera cases are on the rise, with 47% more cases reported to WHO in 2014 than in 2013. Innovative approaches to control the disease
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Real time quantitative polymerase chain reaction RQ PCR was
2019-05-16
Real-time quantitative polymerase chain reaction (RQ-PCR) was performed to quantify BCR/ABL1 transcript as described previously [1]. The quantitative results were expressed as percent ratios relative to an ABL1 internal control using the following formula (p210 BCR–ABL/ABL1×100×CF) [2]. The level of
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br Voltage gated sodium channels are
2019-05-16
Voltage-gated sodium colorimetric assay are essential for modulating the amplitude and upstroke velocity of the cardiac action potential, which are parameters that are important determinants of impulse propagation and conduction velocity through the myocardium. Functional analyses using patch-cla
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In our study the levels
2019-05-16
In our study, the levels of BALP, PINP and β-CTx in the serum were significantly (pfdps markers indicate that the bone formation and bone absorption occur at the same time in patients with BM. Another feature of our research was that we used BTMs clinically to predict the risk of SREs. We found th
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Cryotherapy related soft tissue injury usually occurs within
2019-05-16
Cryotherapy related soft tissue injury usually occurs within a few weeks postoperatively. Skin necrosis is a significant complication if freezing of the superficial surface occurs. Constant irrigation of the adjacent tissues with warm saline reduces the chance of skin necrosis. Our rate of infection
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In recent years there has been growing interest
2019-05-15
In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR
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After overdrive pacing excitation that is
2019-05-15
After overdrive pacing, excitation that is one lap behind (the second beat after the stimulus) is caused by several mechanisms. One is the prolonged conduction time that is longer than the TCL due to a long conduction pathway and/or slow conduction. The other is the dual-loop reentry [12]. The excit
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The results of our initial
2019-05-15
The results of our initial cross-sectional analyses assessing the clinical characteristics of the patients participating in ASSAF-K are shown in Table 1. As compared with the “Fushimi AF Registry,” considered a representative Japanese AF registry with an initial registration of 3183 patients [28], t
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widely used nationally En la segunda publicaci n Entrevista
2019-05-15
En la segunda publicación, “Entrevista con don Carlos Pérez”, éste un ciudadano argentino ficticio recién llegado de Bogotá durante un viaje por Sudamérica, menciona widely used nationally José María Rivas Groot a propósito de su “Estudio pre liminar”, en el Parnaso colombiano publicado en 1888 y lo
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br Planteamientos Previos El presente
2019-05-15
Planteamientos Previos El presente estudio muestra la estrecha relación entre los procesos identitarios y las transformaciones de los contextos migratorios. Centrándose en el caso de los migrantes indígenas de Otavalo (Ecuador) en una de las ciudades del sur de España, la investigación parte de u
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