• A critical link exists between awareness of risk the presenc

  2019-06-10

  

  A critical link exists between awareness of risk, the presence of disease, and steps taken by the patient and clinician to change the natural history of disease. Chronic illnesses such as diabetes mellitus, dyslipidaemia, anaemia and a multitude of endocrinological and rheumatological diseases are r

• br Monitoring coagulation levels Coagulation levels

  2019-06-10

  

  Monitoring coagulation levels Coagulation levels can be monitored after warfarin treatment by measuring the prothrombin time (PT). However, monitoring is not needed for novel anticoagulants because these drugs have a much wider therapeutic range than warfarin. Nonetheless, in patients at high ri

• The pre procedural venogram showed

  2019-06-10

  

  The pre-procedural venogram showed total occlusion of the left BCV and the formation of an acute angle between the right BCV and SVC caused by tuberculosis-induced lung destruction (Fig. 1A and B). We adopted a right-sided venous approach via the right subclavian vein (SCV) for a single chamber. Ini

• br Introduction Once metastatic breast

  2019-06-10

  

  Introduction Once metastatic breast cancer Boc-Pro-OH are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade the b

• Interpretation Patient centred medical education can improve

  2019-06-06

  

  Interpretation Patient-centred medical education can improve overall satisfaction and sustained disease-specific knowledge in patients in Uganda. Our results show that printed booklets are accepted by patients and feasible to implement in a LMIC outpatient setting. Funding Trishul Siddharthan recei

• br Conflict of interest br Case presentation A year

  2019-06-06

  

  Conflict of interest Case presentation A 64-year-old female presented to the emergency room with persistent dizziness that began early that morning. She had a 30-year history of palpitations and known electrocardiogram (ECG) abnormalities. Her pulse was irregular at 130–270min−1 and blood pres

• Programmed death ligand PD L

  2019-06-06

  

  Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed

• br Bisphosphonate use and breast cancer risk BPs are

  2019-06-06

  

  Bisphosphonate use and breast cancer risk BPs are commonly used in the management of postmenopausal osteoporosis. They consist of two phosphate groups, which give them a high affinity to bone. They attach to bone at exposed calcium hydroxyapatite binding sites, which are most accessible at sites

• HIV counselling and testing is

  2019-06-06

  

  HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase

• gadobutrol Two other groups subsequently published further

  2019-06-06

  

  Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant

• br Methods The study population

  2019-06-06

  

  Methods The study population comprised 150 patients who underwent implantations of Medtronic dual chamber pacemakers and who had maintained both atrial and ventricular sensing (either in DDD, DDI, or VDD modes) from March 2008 to October 2010. The implanted glutathione peroxidase generators were

• The benign exostoses in TRPS have a recognized

  2019-06-06

  

  The benign exostoses in TRPS have a recognized malignant potential which have been shown to develop into chondrosarcomas [4,13]. Both our index case and his mother demonstrated de novo high grade osteosarcoma. To our knowledge, this occurrence has not been described anywhere within the literature.

• In the current era nearly all cases of hormone receptor

  2019-06-06

  

  In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud

• br Disclosures and funding sources

  2019-06-06

  

  Disclosures and funding sources Conflicts of interest Introduction In 1994, Leenhardt et al. first described electrocardiogram (ECG) findings of torsades de pointes and QT prolongation in patients without demonstrable structural AMG 925 disease, with the torsades de pointes initiated by sho

• br Descripci n de las variantes Las

  2019-06-06

  

  Descripción de las variantes Las variantes en los dos poemas estudiados a veces son leves: puntuación, acentuación o actualización de la ortografía. Pero cuando las acotaciones implican cambio de léxico o la sustitución de una parte o de un verso completo, constituyen un problema textual que ayud

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